Today we’re happy to announce that both .NET Framework 4.6.1 and .NET Framework 4.6.2 are officially supported on servers running Microsoft System Center 2012 R2 Virtual Machine Manager (VMM 2012 R2). We have also validated Windows Management Framework 5.0 (WMF 5.0) with Windows Server 2012 R2 computers so that is supported as well. The official TechNet product documentation will be updated shortly.
J.C. Hornbeck, Solution Asset PM
Microsoft Enterprise Cloud Group